Chat interfaces and AI assistants you can run locally or self-host, connected to open or commercial language models.
Active Pro listings from this category appear first. Your sort applies within Pro and Free results.
5ireAI Assistants & ChatFree Electron desktop client for Windows, macOS and Linux that connects OpenAI, Anthropic, Google, Ollama and other providers to MCP tools, prompts and resources, with per-tool approval, a local bge-m3 knowledge base and usage analytics.Open sourceSoftware
Agent ZeroAgent FrameworksAgent Zero is an open-source, MIT-licensed AI agent that works in its own Dockerized Linux workspace with a terminal, browser and desktop apps.Open sourceSelf-hosted
AnythingLLMAI Assistants & ChatAnythingLLM from Mintplex Labs is an MIT-licensed AI app for document chat with citations, agents, MCP tools and scheduled jobs, using local or hosted LLMs, as a desktop app, a multi-user Docker server or a hosted cloud.Open sourceSelf-hostedFreemium
better-chatbotAI Assistants & Chatbetter-chatbot is an open-source AI chat and agent platform with MCP connections, searchable project documents and visual workflows. It supports self-hosting and local or gateway-based model access.Open sourceSelf-hosted
BlinkoNotes & Knowledge ManagementBlinko is a GPL-3.0 note-taking server for quick card notes and longer Markdown notes, with RAG search, AI chat, MCP and an OpenAPI interface. It runs from one Docker image on PostgreSQL; a hosted Blinko Cloud edition is also offered.Open sourceSelf-hostedFreemium
Cherry StudioAI Assistants & ChatAGPL-licensed desktop client for Windows, macOS and Linux that connects 60+ model providers and local servers such as Ollama, and adds agents with folder access, MCP and Skills, knowledge bases, image generation and a local API gateway.Open sourceSoftwareFreemium
CodyncAI Coding Assistants & Agent ToolingCodync is a free Apache-2.0 app that turns the coding agents signed in on your computer into persistent bots. A Rust host drives them over ACP; you chat, approve edits and get notified from iPhone, a desktop app or a terminal.Open sourceSelf-hosted
ContentportMarketing & SEOOpen-source content platform for technical founders that drafts, schedules and manages posts for X (Twitter). It learns your writing style, keeps a posting queue and monitors topics. Hosted at contentport.io, source under AGPL-3.0.Open sourceWeb platformFreemium
EigentAI Assistants & ChatApache 2.0 desktop app built on the CAMEL framework for Windows, macOS and Linux. Run one agent or a coordinated Workforce with your own API keys, local models, MCP servers, Skills and scheduled Automations.Open sourceSelf-hostedFreemium
fullmoonAI Assistants & Chatfullmoon is an open-source SwiftUI app from Mainframe that downloads quantized Llama 3.2 and DeepSeek R1 Distill models and runs them on Apple silicon with MLX Swift. Chats are stored on the device and work without an internet connection.Open sourceSoftware
gooseAI Coding Assistants & Agent ToolingApache-2.0 AI agent written in Rust, with a desktop app, a CLI and an ACP server. It works with 15+ model providers or built-in local inference, connects to MCP extensions and runs reusable recipes. Originally from Block, now hosted by AAIF.Open sourceSelf-hosted
GPT4AllAI Assistants & ChatGPT4All is an MIT-licensed desktop app from Nomic AI that runs GGUF language models locally on Windows, macOS and Linux, with LocalDocs document chat, a local OpenAI-compatible API server and a Python SDK.Open sourceSoftware
Hermes AgentAgent FrameworksMIT-licensed agent from Nous Research that runs in a terminal, desktop app, browser or chat apps. It keeps curated memory, writes and refines its own skills, schedules jobs and works with OpenRouter, Anthropic, OpenAI, local or Nous Portal models.Open sourceSelf-hostedFreemium
IronClawAI Assistants & ChatIronClaw is a MIT or Apache-2.0 Rust AI assistant from NEAR AI. It keeps credentials out of the model, runs tools in WASM sandboxes, and offers a local WebUI, routines, memory and MCP, or paid hosted instances.Open sourceSelf-hostedFreemium
Jarvis AI AssistantAI Voice, Speech & TranscriptionMIT-licensed Electron app for macOS: hold Fn, speak, and cleaned-up text is typed into the active app. Transcription runs locally with Whisper, Parakeet or SenseVoice, or through Deepgram and OpenAI; text cleanup uses Gemini, Ollama and other providers.Open sourceSoftware
KhojAI Assistants & ChatOpen-source personal AI server under AGPL-3.0: semantic search and chat over PDF, Markdown, org-mode, Word and Notion content, with agents, research mode, automations and Obsidian, Emacs and web clients. Khoj Cloud closed in April 2026, so it is self-hosted.Open sourceSelf-hosted
Kortix CompanyOSAgent FrameworksSource-available platform for running AI agents across a company: event-triggered agents, 3,000+ connectors, per-session cloud computers, approvals and audit, from Kortix Cloud or a self-hosted Docker Compose stack.CommercialSelf-hostedFreemium
LeonAI Assistants & ChatLeon is an open-source personal AI assistant that runs from source on your own Linux, macOS or Windows machine. Its 2.0 Developer Preview adds an agent loop with toolkits, layered memory, llama.cpp or cloud models and optional local voice.Open sourceSelf-hosted
LibreChatAI Assistants & ChatLibreChat brings multiple AI providers, custom agents, file interactions, and conversation management into a self-hosted web interface with multi-user access controls.Open sourceSelf-hosted
LobeHubAgent FrameworksLobeHub is a TypeScript agent workspace with tasks, memory, pages and MCP tools. Agents answer in Slack, Discord or Telegram, can drive Claude Code or Codex on your devices, and run in LobeHub Cloud, desktop apps or a Docker Compose stack.Open sourceSelf-hostedFreemium
MikeAI Assistants & ChatMike (MikeOSS) is an AGPL-3.0 legal AI platform with cited document chat, tabular review, contract playbooks, a Word add-in and CourtListener research. It runs on your own Supabase and S3 storage with hosted or local Ollama models.Open sourceSelf-hosted
MorphicSearch EnginesApache-2.0 AI search engine built on Next.js and the Vercel AI SDK. A research agent queries Tavily, SearXNG, Exa, Firecrawl or Brave, reads pages and returns cited answers. Runs with Docker Compose, OpenAI, Anthropic, Gemini or Ollama models.Open sourceSelf-hosted
nanobotAgent FrameworksMIT-licensed personal AI agent from HKUDS that runs as a local or server gateway, answers in a browser, terminal or chat apps, works with files, shell, web and MCP tools, keeps long-term memory and runs scheduled automations.Open sourceSelf-hosted
NanoClawAI Assistants & ChatOpen-source personal AI assistant with a small TypeScript core. Agents run in per-session Docker containers, keys stay in a credential gateway, and channels such as WhatsApp, Telegram, Slack or Discord are added as skills. Claude by default.Open sourceSelf-hostedExplore collections with tools relevant to this category, grouped by deployment, source model or workload.
34 matching tools from this category
38 matching tools from this category
3 matching tools from this category
This category covers chat interfaces and personal assistants that you install on a desktop or host on your own server, then connect to local models or to commercial model APIs. Typical features include conversation history, document upload with retrieval, multi-user access, and connections to external tools through the Model Context Protocol. It differs from agent frameworks because the product is a usable front end out of the box, not a library for building one.
What belongs in this category: Listed products give end users a ready conversational interface or persistent assistant, self-hostable or local, where the model behind it can be chosen or swapped rather than fixed by a single provider.
iThub lists 41 tools in AI Assistants & Chat. 38 of 41 are open source, 34 of 41 can be self-hosted, 40 of 41 have a free, freemium or open-source pricing model and 22 of 41 offer an API.
Recently added: Rakazo, Sugabots, AnythingLLM, GPT4All
Compare Open WebUI and LibreChat →Read a guide to local models and hardware →Explore local LLM inference tools →
Use the resources that match your decision stage. Profile data and linked sources were refreshed through November 10, 2026.
